Devicare IP6 Gold® Powder Mango Passionfruit, immune support formula, 377 g | IP6 Powder with Myo-Inositol, Mango & Passion Fruit Flavor. Vegan, Non-GMO, Gluten-Free Antioxidant Supplement. Made in USA.

(see update below) Early during the course of my remission from APL leukemia, I would occasionally experience symptoms that preceded the original onset of my disease, as well as cutaneous eruptions that were reported to presage a relapse. As the recommended option for a full relapse would be bone marrow transplant (a grueling procedure, very risky at my age), I opted to instead search for alternative therapies. Though I am not well-versed in oncology, my training in neuroscience at least made it easy to read the scientific literature on the subject. A fellow colleague had mentioned IP6, being studied for its anti-cancer effect by Dr. Shamsuddin's laboratory at the University of Maryland. The literature looked very good (many peer reviewed papers, including work from several research groups other than Dr. Shamsuddin's), and given that IP6 is naturally present in the human body, I decided to give it a try. I started with the formulation sold at Whole Foods because it was most convenient and I like their products for other vitamins and supplements. For me, the effect was dramatic. My energy immediately improved and the cutaneous symptoms completely disappeared. The only downside was that after one week of taking IP6 I developed some mild muscle cramping (binding of calcium by IP6 should theoretically cause cramping) and a slight negative effect on mood, so I opted to go on a modified schedule of 5 days on, 25 days or so off, which actually mimicked the dosing regimen that had been used for one of my chemotherapy drugs. But the muscle cramps would still occur on occasion, and the colleague who originally recommended IP6 suggested that I try Dr. Shamsuddin's formulation, which was reported to have no effects on mood or muscular side effects (possibly as a result of the formulation, i.e. a balance between inositol and IP6). I switched and he was right! Because the 5 days on, 25 days off was keeping me healthy and I like to minimize the extent to which I take anything, I've stayed with that approach and am still leukemia-free at the 4-year point. I firmly believe that it is time for large clinical trials of IP6, but the flaw in developing treatments in the U.S. is that the trials are unlikely to be performed when no large pharmaceutical company is willing to foot the bill. They won't, because IP6 is cheap. Thus, it is my opinion that Dr. Shamsuddin is really heroic in his mission to make this safe and effective option available to cancer patients and survivors like me. Update: 4/14/2017. I am more convinced than ever that this product has saved my life. Late last summer and into the fall, I was travelling extensively and had run out of my supply of IP6. I'd been doing so well, that I decided not to worry and skipped nearly 3 months. In early November, I crashed, was not feeling well at all and developed the worrisome cutaneous symptoms that resemble leukemia cutis. My oncologist conducted blood work, which showed a normal cell profile, but the crucial test results had not come in on the day of our appointment. Despite her view that I appeared to be doing fine, I knew that I wasn't and restarted my regimen of IP6. Over the next few weeks, I began to return to normal. At my next scheduled visit (last Monday), she discovered to her horror and to my great dismay, that she had neglected to check the definitive test for APL leukemia (what is known as a PCR test for the fusion transcript, PML-RARA) from my last visit, and it was positive! Then began the agonizing week-long wait for my current status to be revealed - I could logically believe that how I felt (great) and the fact that I had resumed Dr. Shamsuddin's IP6 regimen had done the trick, but I woke up many nights quite sure that what they told me and what I'd read was correct (once the PML-RARA test is positive, it relentlessly leads to a relapse unless new chemotherapy is begun; and even then, a 2nd remission usually doesn't hold). Well, this morning the results came back, and the test was negative! If this was a case report, it would be considered so remarkable that the New England Journal of Medicine would be a suitable venue for publication. To convert from a positive PML-RARA test to negative without chemo is unheard of. Perhaps now I can convince my oncologist that IP6 is something all her patients should be on.

I am a competitive athlete. I cannot give a high enough rating for this product ++++++++++. My results are not amazing, they are absolutely ASTOUNDING. My own results are so incredible it's ***hard to believe***. Without a doubt massive results. Of course, if you sit on a couch all day you might not notice anything, You can save a little $/oz over the smaller sized offering and you get a sold fruity flavor which I find appealing. The flavored version is delish. Morning: Tablespoon IP6, scoop of protein powder and some Ovaltine with some milk. Want a frozen smoothie? IP6, protein powder, frozen banana, peanut butter and a tray of ice. Add whatever you want (or not), it's your choice,

Updated 2-24-21, attention: maker of product. Please go back to the prior formula before this new improved flavor. The new improved is horrible and sickeningly sweet. It cannot be camouflaged. I’m going back to enzymatic therapy brand if they don’t fix this flavor. Beware Flavor is terrible folks but Im fairly certain my liver and other organs give this a thumbs up!! HOW TO GET IT DOWN!!?? I suggest 1st drink your normal smoothie! Enjoy that before u add scary ip6 flavor, ok? Don’t mix the io6 in there. Later after ur shake then put 1/4 banana, vanilla ice cream, slimfast vanilla liquid (blend in your nutribullet blender!). then add two teaspoons io6 to it , blend, mix well, then still may need to chase with water. You can always take the capsules? I took 10-15 per day as therapeutic recommendation however always check with ur doctor! I would take this at least an hour away from prescribed medication . I think blood pressure medicine u cannot take with grapefruit so please check on this as well. Ip6 lessens ur calcium so u need extra calcium via pills or through diet. It Also depletes your iron. I take iron in bis glycinate form so no stomach upset! I do not take iron supplements that contain ascorbic acid to avoid stomach distress. Though I will consume orange juice with my iron pills as it aides absorption. If you don’t take an iron supplement while on ip6 u will become very lethargic and fatigued, beware!

Consistent product. Love my ip6.

Since I believe so much in IP6Gold and have first hand experience in what it has done for me, I researched it and found that at a dose for those with active cancer, suggested therapeutic dosage is 6-12 pills twice a day. So I increased my dosage and then found that the powder form has a scoop in it that when mixed with water is the same as 8 pills, and it is so much easier to take especially when in a hurry. this powder form has a bit of stevia in it for taste but since I am not a sweet taste person, I would have rather not had a sweetener in it but it still tastes extremely good. Although I've read that it is best absorbed on an empty stomach, a friend would put it on his cereal in the mornings for a sweetener. Anyway, this is a fantastic product and a great alternative to one that has trouble swallowing and/or doesn't like taking pills. At a lower dosage, my friend just mixes half a scoop equaling 4 capsules. I could go on and on about what a difference this IP6gold has changed my life having had cancer. I will take it forever.

I started taking this product 3 months ago after purchasing for my Aunt who has bone cancer. Dr. Shamsuddin called me and gave instructions on how many pills to give her and said it is an excellent supplement for me to take as well to help me feel well and prevent cancer. I started taking 2 caps twice a day. A month after taking it I experienced a Herxhiemer Reaction in relation to Lyme disease and related co-infections. This is so good it even killed the bacteria from Lyme and 2 co-infections. I have now had 3 Herxhiemer Reactions and feel better every day.I am so excited to know that I will never need to take another antibiotic again for the Lyme disease. I will never stop taking IP-6 Gold either. Powder is a little less expensive and I can put it in my smoothie or drink of my choice. It even helped my cat when she was injured by another cat and developed a serious abscess on her leg, she wouldn't play, or eat much or drink, she would not use her leg either. I tried her on IP-6 and 3 days later she was playing again, her leg is drying up and she is walking like normal. I am so excited about this product. And Dr. Shamsuddin backs up this product himself. I am sold!

I have been using this IP6 for some time and have always thougfht it was easy to take due to the pleasant taste. The latest order December 2018 was the normal tropical floavor I always order but it tastes horrible. It is now bitter. It makes me question what is in it now. It is to prevent cancer recurrance so I am worried about what I am taking. I guess it might be time to switch brands. A loyal customer who is now very disappointed.

I don't have cancer. I did have a (genetic birth defect) heart valve issue that was extreme and nearly killed me. During the time I was dying, before open heart surgery, and most my nutrients and oxygen were ending up as edema and inflammation instead of staying in the veins to make it to my body using them, once in a while I would take this IP6 Gold. Not often because it was pricey and I didn't like the taste and I wasn't healthy enough to do much for myself let alone consistently. But when I did, it gave me a bit more energy in the day, enough that I would consciously notice having it. Three things had "measurably" -- at the time VERY noticeable -- positive effects for me during that time. Normally taking supplements, I don't 'feel' a difference. Because my energy was so low then I really could feel positive effects. This stuff is one. Second: Co-Q10 (ubiquinol or higher dosage ubiquinone) did not make me feel more energy but had a dramatic impact on my ability to get movement with less heart stress and less gasping for air, and if I took it in late afternoon I would not sleep until many hours later, not in a bad way, I didn't feel wired, I merely didn't feel tired as if my body organs had more energy to last longer perhaps. (I avoid it if it's late afternoon only 'cause I gotta work the next morning so I need to sleep on time!) The third is magnesium oil, slathering it all over my (large) skin surface, giving it 15 minutes, then showering it off. That's a real PITA so I don't do it much. But when I have, esp. a few days running, it had a significant "up" in my daily energy, consciously-noticeable. Ironically I don't think I ever tried all three of these at the same time. I was kind of overwhelmed by merely getting through each day, and alone, so in retrospect it wasn't the most logical course of actions, but oh well. I am vastly better now after a last-minute (probably had a week to live) open heart surgery that changed my life for the better. But now I'm a 'true believer' in the things that helped me most during my worst times, and that I could really FEEL and measurably notice energy or improvement in my body with. This stuff really seemed like my body was getting a good effect from it. I was only taking one scoop in the early day with juice, as the dosage. I just realized the other day I should buy more, and see if I can still feel a difference even when so much healthier.

I don't know why but this just taste so bad and its so hard for me to drink