VetoquinolZylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg

Seriously buy this. Our pug has evening anxiety ever since the 4th of July. The vet prescribed Trazodone which made it so much worse and then she gave her Gabapentin which knocked her out and we don’t want to sedate her. The vet suggested to give this product a try and I can’t even believe how well it works, I would assume it was a script if I hadn’t known. We give it to her around 3:30 and by 5 she’s calm and chill, she is a little sleepy but more relaxed. It does not last all day. She is more like her normal self around 9:30 which is great bc it’s bedtime.

Okay, this is going to sound like it was written by a relative, but I'm just your normal, average animal freak with five resident dogs and seven cats (two are fosters). Over the years we've had probably a hundred or more animals in our home, and we tend to adopt the misfits. Mango, our overanxious, neurotic rat terrier is one of our bigger challenges. She has to modes: catatonic and, as my friend put it, "tiny psycho dog." Over the years, we've done any number of behavioral, homeopathic, and medical interventions with only modest success. After a series of very volatile outbursts, our vet put her on a strong antianxiety medication before. We were thinking we may need to prepare ourselves for euthanasia, something we aren't in a rush to do, but after three years and thousands of dollars, we were running low on options. The drugs worked, but she was so zonked out there were nights we had to literally carry her upstairs. We knew we had to wean her off of the drugs but we were apprehensive about her reverting back to her old ways. The vet said one of the other vets had good luck with Zylkene, and said while it's spendy, maybe it was worth a shot. Since she's been completely off the drugs and exclusively on the Zylkene (about 3 months), she's gone from several occurrences of attacking the other animals (and occasionally is) a DAY to maybe twice in the past three months, and very easy to redirect to preferred behavior. I truly believe this stuff has saved the life of the dog who stole my heart. She's a confident and affectionate little girl who not only doesn't fight with her siblings, but actually cuddles with them! Remarkable! I haven't had the same luck with our other anxious dogs, but if say it's worth a shot of you're at wit's end.

This is not a sedative, so it's not going to make your dog sleep nor have a huge startling effect on behavior. I've been using for almost a month and I notice a slightly mellower dog. I purchased looking for something that would help during summer thunderstorms, as the dog in question has an extreme case of storm phobia. If the storm stays in the far distance, she doesn't seem to react as much. If it's right on top of us, she's still pretty freaked out, so this certainly isn't a silver bullet. Still, she seems a little less worried/anxious in general.Four stars because the cost is so high for what, to me, is only a slight improvement. I'm not sure I'll use it after the summer due to cost, and I know many of my friends want to try it but simply can't afford it as a maintenance drug for their pet. Here's hoping the manufacturers drop the price to make it more accessible (I suspect they'd sell a lot more).

This product is excellent and I’ve tried cheaper versions and other natural versions but this one is the best. I do believe it is way too expensive though. If I could find a less expensive seller I would but it appears this is the only one that sells this. And almost every time I order this product it gets lost in shipping and is extremely delayed. I don’t believe it’s the fault of the seller. So order early and ahead of needing your next supply because it’s delayed up to a week and sometimes completely lost and I have to reorder.

I started using Zylkene eight days before the fireworks started. The recommended dose for each dog ( 19 pounds and 14.5 pounds) was 150 mg. So I bought the 225 mg capsules and cut the capsules in half so each dog received approximately 112 mg every morning. On July 3rd and 4th, when our usually quiet neighborhood sounds like a war zone for hours, I gave an additional dose in the evening. In previous years, we went to the basement and played Music Through a Dog's Ear very loudly to drown out the outside noise. However, the dogs still became frantic and could not be comforted until the noise stopped about 1 or 2 AM. Obviously, this was stressful for us as well.Zylkene changed my dogs' response to a known severe stressors. We still had to go down to the basement, but our dogs did not become frantic. There was some panting and restlessness, but they could be held and comforted through the worst of the noise. We were able to watch TV just like it was a normal evening. One dog even fell asleep on my lap. We also noticed the dogs tolerated intermittent (legal) firework noise while outside without immediately running to door to get in the house. We gave (and they readily took) treats as positive reinforcement for tolerating the noise. Then last night we had a severe thunderstorm in the middle of the night. Without getting up to get the Thundershirts or starting the calming music, both dogs reacted to the noise but, again, did not become frantic. We were able to hold and comfort them until the storm passed and everyone could fall asleep again. We will continue Zylkene for the rest of summer until the thunderstorm season has passed.

This had 0 effect on my dog’s anxiety. I’ve been using this for the past 3 weeks and there was no change whatsoever. It’s unfortunate how expensive this item is and it’s non-returnable.