How tight are these screwed, and can they be opened by hand without a screwdriver?

They can be opened and closed by hand.

Why are we not supposed to tighten these by hand?

I have atleast 50 of these type miniature glass vials in different shapes, I use a toothpick when closing the top to prevent any cross-threading that can damage the piece, you can use your fingers if you like, just have to screw it on gently.

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Description

✨ Wear Your Memories, Share Your Story! ✨

DURABLE DESIGN - Stainless steel chains that resist rust and wear.
CRAFT YOUR STORY - Unleash your creativity with 12 customizable glass vials.
TIMELESS ELEGANCE - Retro style meets modern charm for every occasion.
MEANINGFUL KEEPSAKES - Perfect for storing memories, from ashes to essential oils.
GIFT OF PERSONALIZATION - Create heartfelt gifts for loved ones on any special day.

The Bonuci 12 Pcs Glass Vial Necklace set includes 12 empty glass charms and 12 durable stainless steel snake chains, perfect for DIY jewelry making. Each vial can hold small sentimental items, making it an ideal choice for personalized gifts or unique fashion statements. The retro style adds a touch of elegance, suitable for various occasions.